Owner F. Hoffmann-La Roche AG

Inventors Gong, Leyi; Abbot, Sarah C.; Buettelmann, Bernd; Tan, Yun-Chou; Boice, Genevieve N.; McCaleb, Kristen Lynn; Goldstein, David Michael; Hogg, Joan Heather; Iyer, Pravin

Agent Spruson & Ferguson

Pub. Number AU-A-2008250049

PCT Pub. Number WO2008/138920

Priority 60/930,054 14.05.07 US

Filing date 13 May 2008

Wipo publication date 20 November 2008

C07D 215/48 (2006.01) Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

A61K 31/4375 (2006.01)

A61K 31/47 (2006.01) - Quinolines

A61K 31/4709 (2006.01) - Non-condensed quinolines containing further heterocyclic rings

A61P 3/00 (2006.01) Drugs for disorders of the metabolism

A61P 25/00 (2006.01) Drugs for disorders of the nervous system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 37/00 (2006.01) Drugs for immunological or allergic disorders

C07D 401/06 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 405/06 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 405/12 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 413/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07F 7/18 (2006.01) Compounds containing elements of the 4th Group of the Periodic System