Owner Exelixis, Inc.

Inventors Aay, Naing; Kim, Moon Hwan; Brown, S. David; Du, Hongwang; Zhou, Peiwen; Kearney, Patrick; Huang, Ping; Kane, Brian; Xu, Wei; Pack, Michael; Chan, Wai Ki Vicky; Koltun, Elena S.; Tsuhako, Amy L.

Agent Davies Collison Cave

Pub. Number AU-A-2008244490

PCT Pub. Number WO2008/133955

Priority 60/926,362 25.04.07 US

Filing date 25 April 2008

Wipo publication date 6 November 2008

C07D 239/36 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

A61K 31/513 (2006.01) - having oxo groups directly attached to the heterocyclic ring, e.g. cytosine

A61P 35/00 (2006.01) Antineoplastic agents

C07D 213/64 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 407/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group

C07D 409/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 409/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 413/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms