Owner The Brigham and Women's Hospital, Inc.

Inventors Comstock, Laurie E.; Coyne, Michael J.; Tzianabos, Arthur O.; Weinacht, Katja G.; Kasper, Denis L.

Agent Davies Collison Cave

Pub. Number AU-B-2008243143

Parent 2003218144

Filing date 6 November 2008

Wipo publication date 27 November 2008

Acceptance publication date 4 October 2012

C12N 15/09 Mutation or genetic engineering - Recombinant DNA-technology

A61K 31/7088 - Compounds having three or more nucleosides or nucleotides

A61K 38/00 Medicinal preparations containing peptides

A61K 48/00 Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 1/00 Drugs for disorders of the alimentary tract or the digestive system

A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 37/02 Drugs for immunological or allergic disorders

C07K 14/195 Peptides having more than 20 amino acids - from bacteria

C07K 14/32 Peptides having more than 20 amino acids

C07K 14/47 Peptides having more than 20 amino acids

C07K 16/18 Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against material from animals or humans

C07K 19/00 Hybrid peptides

C12N 1/15 Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12P 19/04 Preparation of compounds containing saccharide radicals

C12Q 1/04 Measuring or testing processes involving enzymes or micro-organisms - Determining presence or kind of micro-organism