Owner Solvay Pharmaceuticals B.V.

Inventors Stoit, Axel; Terwel, Louise, heir of Reinders Jan H. (deceased); Kruse, Cornelis G.; Coolen, Hein K.A.C.

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-A-2008240704

PCT Pub. Number WO2008/129054

Priority 60/913,584 24.04.07 US; 07106814.2 24.04.07 EP

Filing date 23 April 2008

Wipo publication date 30 October 2008

A61K 31/439 (2006.01) - the ring forming part of a bridged ring system, e.g. quinuclidine

A61K 31/4427 (2006.01) - containing further heterocyclic ring systems

A61K 31/4439 (2006.01)

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

C07D 401/04 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 413/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 453/02 (2006.01) Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids

C07D 471/08 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups