Owner Amgen Inc.

Inventors Du, Bingfan; White, Ryan; Schenkel, Laurie; Deak, Holly L.; Cee, Victor J.; Olivieri, Philip R.; Panter, Kathleen; Romero, Karina; Geuns-Meyer, Stephanie D.; Hodous, Brian L.; Nguyen, Hanh Nho; Martin, Mathew W.

Agent Shelston IP

Pub. Number AU-B-2008236670

PCT Pub. Number WO2008/124083

Priority 60/922,205 05.04.07 US

Filing date 3 April 2008

Wipo publication date 16 October 2008

Acceptance publication date 1 December 2011

C07D 401/04 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61K 31/502 (2006.01) - ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine

A61P 35/00 (2006.01) Antineoplastic agents

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 409/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 493/04 (2006.01) Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system

C07D 495/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms