Substituted pyrimidodiazepines useful as PLK1 inhibitors

Details for Australian Patent Application No. 2008228303 (hide)

Owner Takeda Pharmaceutical Company Limited

Inventors Luk, Kin-Chun Thomas; Chu, Xin-Jie; Le, Kang; Wovkulich, Peter Michael; Chen, Shaoqing; Cai, Jianping

Agent Davies Collison Cave

Pub. Number AU-B-2008228303

PCT Pub. Number WO2008/113711

Priority 60/919,358 22.03.07 US

Filing date 11 March 2008

Wipo publication date 25 September 2008

Acceptance publication date 19 April 2012

International Classifications

C07D 471/18 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

A61K 31/551 (2006.01) - having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep

A61K 31/5517 (2006.01)

A61P 35/00 (2006.01) Antineoplastic agents

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 487/18 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

Event Publications

17 September 2009 PCT application entered the National Phase

  PCT publication WO2008/113711 Priority application(s): WO2008/113711

10 June 2010 Assignment before Grant

  F. Hoffmann-La Roche AG The application has been assigned to Takeda Pharmaceutical Company Limited

19 April 2012 Application Accepted

  Published as AU-B-2008228303

16 August 2012 Standard Patent Sealed

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