1,4-disubstituted 3-cyano-pyridone derivatives and their use as positive mGluR2 -receptor modulators

Details for Australian Patent Application No. 2008223795 (hide)

Owner Ortho-McNeil-Janssen Pharmaceuticals, Inc Addex Pharma S.A.

Inventors Duvey, Guillaume Albert Jacques; Trabanco-Suarez, Andres Avelino; CidNunez, Jose Maria; Lutjens, Robert Johannes; Macdonald, Gregor James

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-A-2008223795

PCT Pub. Number WO2008/107480

Priority 07103654.5 07.03.07 EP; PCT/ EP2007/052442 15.03.07 EP; 07116402.4 14.09.07 EP

Filing date 7 March 2008

Wipo publication date 12 September 2008

International Classifications

A61K 31/4412 (2006.01) - having oxo groups directly attached to the heterocyclic ring

A61K 31/4418 (2006.01) - having a carbocyclic ring directly attached to the heterocyclic ring, e.g. cyproheptadine

A61K 31/443 (2006.01)

A61K 31/4436 (2006.01)

A61K 31/4439 (2006.01)

A61K 31/444 (2006.01)

A61P 25/22 (2006.01) Drugs for disorders of the nervous system

C07D 213/85 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 401/04 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/06 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/10 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 405/06 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

Event Publications

22 October 2009 PCT application entered the National Phase

  PCT publication WO2008/107480 Priority application(s): WO2008/107480

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