Pyridine or pyrimidine derivative having excellent cell growth inhibition effect and excellent anti-tumor effect on cell strain having amplification of HGFR gene

Details for Australian Patent Application No. 2008217931 (hide)

Owner Eisai R & D Management Co., Ltd.

Inventors Matsushima, Tomohiro; Takahashi, Keiko; Nakagawa, Takayuki; Obaishi, Hiroshi; Funasaka, Setsuo; Shirotori, Shuji

Agent Davies Collison Cave

Pub. Number AU-A-2008217931

PCT Pub. Number WO2008/102870

Priority 2007-044424 23.02.07 JP

Filing date 22 February 2008

Wipo publication date 28 August 2008

International Classifications

C07D 213/75 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/4412 (2006.01) - having oxo groups directly attached to the heterocyclic ring

A61K 31/4427 (2006.01) - containing further heterocyclic ring systems

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/5377 (2006.01)

A61P 35/00 (2006.01) Antineoplastic agents

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

C12Q 1/68 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving nucleic acids

G01N 33/15 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Medicinal preparations

G01N 33/48 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Biological material, e.g. blood, urine

G01N 33/50 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Chemical analysis of biological material, e.g. blood, urine

G01N 33/53 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Immunoassay

G01N 33/574 (2006.01) Investigating or analysing materials by specific methods not covered by groups - for cancer

Event Publications

27 August 2009 PCT application entered the National Phase

  PCT publication WO2008/102870 Priority application(s): WO2008/102870

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