Owner Merck & Co., Inc.

Inventors Hale, Jeffrey J.; Huo, Pei; Yan, Lin; Debenham, John S.; Walsh, Thomas F.; Madsen-Duggan, Christina B.

Agent Spruson & Ferguson

Pub. Number AU-A-2008211259

PCT Pub. Number WO2008/094476

Priority 60/898,602 31.01.07 US; 60/905,690 08.03.07 US

Filing date 25 January 2008

Wipo publication date 7 August 2008

C07D 491/052 (2006.01) Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or

A61K 31/436 (2006.01)

A61P 1/00 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 25/00 (2006.01) Drugs for disorders of the nervous system

C07D 491/16 (2006.01) Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or

C07D 495/16 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms