Owner AstraZeneca AB

Inventors Cox, Rhona Jane; Hunt, Simon Fraser; Sanganee, Hitesh Jayantilal; Meghani, Premji; Bonnert, Roger Victor; Pimm, Austen; De Sousa, Simon; Dickinson, Mark; Burkamp, Frank

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2008204412

PCT Pub. Number WO2008/084223

Priority 60/884,454 11.01.07 US; 60/941,749 04.06.07 US; 60/952,047 26.07.07 US

Filing date 10 January 2008

Wipo publication date 17 July 2008

Acceptance publication date 1 March 2012

C07D 213/80 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/519 (2006.01) - ortho- or peri-condensed with heterocyclic rings

A61P 11/06 (2006.01) Drugs for disorders of the respiratory system

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 471/08 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 519/00 (2006.01) Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or