Owner Alnylam Europe AG

Inventors Kreutzer, Roland; Limmer, Stefan

Agent Griffith Hack

Pub. Number AU-B-2008202208

Parent 2005201044

Filing date 19 May 2008

Wipo publication date 5 June 2008

Acceptance publication date 29 October 2009

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 9/127 (2006.01) Medicinal preparations characterised by special physical form - Liposomes

A61K 31/70 (2006.01) - Carbohydrates

A61K 31/713 (2006.01) - Double-stranded nucleic acids or oligonucleotides

A61K 35/76 (2006.01) Medicinal preparations containing material or reaction products thereof with undetermined constitution

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

A61P 31/12 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 35/00 (2006.01) Antineoplastic agents

C12N 15/11 (2006.01) Mutation or genetic engineering - DNA or RNA fragments

A61K 38/00 (2006.01) Medicinal preparations containing peptides