Owner Genentech, Inc.

Inventors Hillan, Kenneth J; Spencer, Susan D; Phillips, Heidi S; Zhang, Zemin; Frantz, Gretchen; Wu, Thomas D; Polakis, Paul; Williams, P Mickey

Agent Griffith Hack

Pub. Number AU-B-2008202007

Parent 2002330015

Filing date 6 May 2008

Wipo publication date 29 May 2008

Acceptance publication date 16 December 2010

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 31/537 (2006.01) - spiro-condensed or forming part of bridged ring systems

A61K 31/7036 (2006.01)

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 35/00 (2006.01) Antineoplastic agents

A61P 35/02 (2006.01) Antineoplastic agents

A61P 35/04 (2006.01) Antineoplastic agents

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07K 14/47 (2006.01) Peptides having more than 20 amino acids

C07K 16/30 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C07K 16/32 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C07K 19/00 (2006.01) Hybrid peptides

C12P 21/08 (2006.01) Preparation of peptides or proteins - Monoclonal antibodies