Owner F. Hoffmann-La Roche Ltd.

Inventors Moestrup, Soren; Graversen Jonas

Agent Pizzeys

Pub. Number AU-B-2008201887

Parent 2002213843

Filing date 30 April 2008

Wipo publication date 22 May 2008

Acceptance publication date 30 June 2011

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 38/47 (2006.01) Medicinal preparations containing peptides

A61K 47/14 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Esters of carboxylic acids

A61K 47/24 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen or sulfur

A61K 47/28 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Steroids

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 7/00 (2006.01) Drugs for disorders of the blood or the extracellular fluid

A61P 9/10 (2006.01) Drugs for disorders of the cardiovascular system

C07K 14/775 (2006.01) Peptides having more than 20 amino acids

C07K 19/00 (2006.01) Hybrid peptides

C12N 1/15 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 15/62 (2006.01) Mutation or genetic engineering - DNA sequences coding for fusion proteins

C12P 21/02 (2006.01) Preparation of peptides or proteins - having a known sequence of two or more amino acids, e.g. glutathione