Owner Georgia State University Research Foundation, Inc. The University of North Carolina at Chapel Hill Werbovetz, K. Brun, R.

Inventors Ismail, Mohamed A; Tidwell, Richard R; Werbovetz, Karl; Wilson, W David; Hu, Laixing; Boykin, David W; Brun, Reto; Arafa, Reem K

Agent Griffith Hack

Pub. Number AU-A-2008200076

Priority 11/698,257 25.01.07 US

Filing date 8 January 2008

Wipo publication date 14 August 2008

C07D 213/78 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/155 (2006.01) - Amidines (), e.g. guanidine (HNC(NH)NH), isourea (HNC(OH)NH), isothiourea (HNC(SH)NH)

A61K 31/341 (2006.01) - not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine

A61K 31/4178 (2006.01)

A61K 31/4418 (2006.01) - having a carbocyclic ring directly attached to the heterocyclic ring, e.g. cyproheptadine

A61K 31/443 (2006.01)

A61K 31/4439 (2006.01)

A61K 31/444 (2006.01)

A61K 31/4965 (2006.01) - Non-condensed pyrazines

A61K 31/505 (2006.01) - Pyrimidines

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61P 33/02 (2006.01) Antiparasitic agents

A61P 33/06 (2006.01) Antiparasitic agents

C07C 257/18 (2006.01) Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines

C07C 279/18 (2006.01) Derivatives of guanidine, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups

C07D 213/26 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/58 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/61 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 239/26 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/28 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 241/28 (2006.01) Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D 307/56 (2006.01) Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 405/14 Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom