Methods of selecting and producing modified toxins, conjugates containing modified toxins and uses thereof

Details for Australian Patent Application No. 2007339753 (hide)

Owner Osprey Pharmaceuticals USA, Inc.

Inventors McDonald, John R.; McIntosh, Laura M.; Coggins, Philip J.; Su, Hongsheng

Agent Spruson & Ferguson

Pub. Number AU-A-2007339753

PCT Pub. Number WO2008/080218

Priority 60/878,166 29.12.06 US; 60/965,977 22.08.07 US

Filing date 17 December 2007

Wipo publication date 10 July 2008

International Classifications

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 11/00 (2006.01) Drugs for disorders of the respiratory system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 37/06 (2006.01) Drugs for immunological or allergic disorders

C07K 14/245 (2006.01) Peptides having more than 20 amino acids

C07K 14/25 (2006.01) Peptides having more than 20 amino acids

C07K 14/475 (2006.01) Peptides having more than 20 amino acids

C07K 14/52 (2006.01) Peptides having more than 20 amino acids

C07K 16/00 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C07K 19/00 (2006.01) Hybrid peptides

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 9/24 (2006.01) Enzymes, e.g. ligases (6.) - acting on glycosyl compounds (3.2)

C12N 15/13 (2006.01) Mutation or genetic engineering - Immunoglobulins

C12N 15/18 (2006.01) Mutation or genetic engineering

C12N 15/19 (2006.01) Mutation or genetic engineering - Interferons

C12N 15/56 (2006.01) Mutation or genetic engineering - acting on glycosyl compounds (3.2), e.g. amylase, galactosidase, lysozyme

C12N 15/62 (2006.01) Mutation or genetic engineering - DNA sequences coding for fusion proteins

C12N 15/63 (2006.01) Mutation or genetic engineering - Introduction of foreign genetic material using vectors

C12P 21/02 (2006.01) Preparation of peptides or proteins - having a known sequence of two or more amino acids, e.g. glutathione

C12Q 1/00 (2006.01) Measuring or testing processes involving enzymes or micro-organisms

C12Q 1/68 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving nucleic acids

G01N 33/68 (2006.01) Investigating or analysing materials by specific methods not covered by groups - involving proteins, peptides or amino acids

Event Publications

16 July 2009 PCT application entered the National Phase

  PCT publication WO2008/080218 Priority application(s): WO2008/080218

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