Owner KYORIN PHARMACEUTICAL CO., LTD. TEIJIN Pharma Limited

Inventors Fujita, Kenji; Kobayashi, Fumiyoshi; Kobayashi, Shinji; Komatsu, Kanji; Nakamura, Ayako; Asahina, Yoshikazu; Yamamoto, Masanori; Ide, Tomohiro; Fukuda, Yasumichi

Agent Griffith Hack

Pub. Number AU-A-2007337382

PCT Pub. Number WO2008/078674

Priority 2006-348222 25.12.06 JP; 2007-057427 07.03.07 JP

Filing date 21 December 2007

Wipo publication date 3 July 2008

C07D 213/80 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/415 (2006.01) - 1,2-Diazoles

A61K 31/42 (2006.01) - Oxazoles

A61K 31/421 (2006.01) - 1,3-Oxazoles, e.g. pemoline, trimethadione

A61K 31/425 (2006.01) - Thiazoles

A61K 31/426 (2006.01) - 1,3-Thiazoles

A61K 31/428 (2006.01) - condensed with carbocyclic rings

A61K 31/433 (2006.01) - Thiadiazoles

A61K 31/437 (2006.01)

A61K 31/4375 (2006.01)

A61K 31/44 (2006.01) - Non-condensed pyridines

A61K 31/4402 (2006.01) - only substituted in position 2, e.g. pheniramine, bisacodyl

A61K 31/4406 (2006.01) - only substituted in position 3, e.g. zimeldine

A61K 31/4409 (2006.01) - only substituted in position 4, e.g. isoniazid, iproniazid

A61K 31/4439 (2006.01)

A61K 31/455 (2006.01) - Nicotinic acid, i.e. niacin

A61K 31/47 (2006.01) - Quinolines

A61K 31/472 (2006.01) - Non-condensed isoquinolines, e.g. papaverine

A61K 31/4965 (2006.01) - Non-condensed pyrazines

A61K 31/50 (2006.01) - Pyridazines

A61K 31/505 (2006.01) - Pyrimidines

A61K 31/519 (2006.01) - ortho- or peri-condensed with heterocyclic rings

A61P 3/04 Drugs for disorders of the metabolism