Inhibitors of histone deacetylase and prodrugs thereof

Details for Australian Patent Application No. 2007335216 (hide)

Owner MethylGene Inc.

Inventors Deziel, Robert; Ajamian, Alain

Agent Spruson & Ferguson

Pub. Number AU-A-2007335216

PCT Pub. Number WO2008/074132

Priority 60/870,768 19.12.06 US

Filing date 19 December 2007

Wipo publication date 26 June 2008

International Classifications

C07C 311/21 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

A61K 31/10 (2006.01)

A61K 31/16 (2006.01) - Amides, e.g. hydroxamic acids

A61K 31/17 (2006.01) - having the group NC(O)N or NC(S)N, e.g. urea, thiourea, carmustine

A61K 31/18 (2006.01) - Sulfonamides

A61K 31/34 (2006.01) - having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide

A61K 31/381 (2006.01) - having five-membered rings

A61K 31/433 (2006.01) - Thiadiazoles

A61K 31/435 (2006.01) - having six-membered rings with one nitrogen as the only ring hetero atom

A61P 35/00 (2006.01) Antineoplastic agents

C07C 259/10 (2006.01) Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups

C07C 275/42 (2006.01) Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups

C07C 317/44 (2006.01) Sulfones

C07D 285/135 (2006.01) Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups

C07D 307/54 (2006.01) Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 333/34 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 333/62 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

Event Publications

2 July 2009 PCT application entered the National Phase

  PCT publication WO2008/074132 Priority application(s): WO2008/074132

19 May 2011 Assignment before Grant

  MethylGene Inc. The application has been assigned to MethylGene Inc.

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