Substituted N-phenylmethyl - 5-oxo-proline-2-amides as P2X7-receptor antagonists and their methods of use

Details for Australian Patent Application No. 2007271182 (hide)

Owner Glaxo Group Limited

Inventors Walter, Daryl Simon; Chambers, Laura J; Senger, Stefan; Gleave, Robert

Agent Davies Collison Cave

Pub. Number AU-B-2007271182

PCT Pub. Number WO2008/003697

Priority 0613473.8 06.07.06 GB; 0622825.8 15.11.06 GB; 0711439.0 13.06.07 GB; 0705263.2 19.03.07 GB

Filing date 3 July 2007

Wipo publication date 10 January 2008

Acceptance publication date 15 March 2012

International Classifications

C07D 207/28 (2006.01) Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

A61K 31/4015 (2006.01) - having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide

A61K 31/402 (2006.01) - 1-aryl-substituted, e.g. piretanide

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07D 401/06 (2006.01) Heterocyclic compounds containing two or more hetero rings

Event Publications

15 January 2009 PCT application entered the National Phase

  PCT publication WO2008/003697 Priority application(s): WO2008/003697

15 March 2012 Application Accepted

  Published as AU-B-2007271182

12 July 2012 Standard Patent Sealed

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