Hydroxylated and methoxylated cyclopenta [D] pyrimidines as AKT protein kinase inhibitors

Details for Australian Patent Application No. 2007269060 (hide)

Owner Array BioPharma Inc. Genentech, Inc.

Inventors Zhang, Birong; Kallan, Nicholas C.; Blake, James F.; Bencsik, Josef R.; Xiao, Dengming; Chabot, Christine; Xu, Rui; Banka, Anna L.; Schlachter, Stephen T.; Wallace, Eli M.; Mitchell, Ian S.; Liang, Jun; Safina, Brian; Spencer, Keith Lee; Do, Steven

Agent Pizzeys

Pub. Number AU-A-2007269060

PCT Pub. Number WO2008/006040

Priority 60/818,718 06.07.06 US

Filing date 5 July 2007

Wipo publication date 10 January 2008

International Classifications

C07D 239/70 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

A61K 31/517 (2006.01) - ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine

A61P 35/00 (2006.01) Antineoplastic agents

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 407/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group

C07D 409/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 409/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

Event Publications

22 January 2009 PCT application entered the National Phase

  PCT publication WO2008/006040 Priority application(s): WO2008/006040

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