Owner Janssen Pharmaceutica N.V.

Inventors Letavic, Michael A.; Keith, John M.; Stocking, Emily M.

Agent Shelston IP

Pub. Number AU-A-2007265239

PCT Pub. Number WO2008/002817

Priority 60/806,165 29.06.06 US

Filing date 21 June 2007

Wipo publication date 3 January 2008

C07C 217/62 (2006.01) Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton

A61K 31/435 (2006.01) - having six-membered rings with one nitrogen as the only ring hetero atom

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 31/535 (2006.01) - having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines

A61P 25/24 (2006.01) Drugs for disorders of the nervous system

C07C 321/28 (2006.01) Thiols, sulfides, hydropolysulfides or polysulfides

C07D 211/38 (2006.01) Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 213/64 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/65 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 241/08 (2006.01) Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D 295/12 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms