Substituted isoindoles as bace inhibitors and their use

Details for Australian Patent Application No. 2007261749 (hide)

Owner AstraZeneca AB

Inventors Kolmodin, Karin; Kers, Annika; Rakos, Laszlo; Edwards, Phil; Rotticci, Didier; Ohberg, Liselotte; Patel, Sahil; Murray, Christopher; Holenz, Jorg; Sylvester, Mark; Arnold, James; Berg, Stefan; Chessari, Gianni; Congreve, Miles

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2007261749

PCT Pub. Number WO2007/149033

Priority 60/815,800 22.06.06 US; 60/891,242 23.02.07 US; 60/818,557 05.07.06 US

Filing date 20 June 2007

Wipo publication date 27 December 2007

Acceptance publication date 3 November 2011

International Classifications

C07D 209/44 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

A61K 31/4035 (2006.01)

A61K 31/4433 (2006.01)

A61K 31/4439 (2006.01)

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

C07D 401/10 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/10 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 407/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group

Event Publications

8 January 2009 PCT application entered the National Phase

  PCT publication WO2007/149033 Priority application(s): WO2007/149033

15 September 2011 Assignment before Grant

  Astex Therapeutics Ltd; AstraZeneca AB The application has been assigned to AstraZeneca AB

3 November 2011 Application Accepted

  Published as AU-B-2007261749

1 March 2012 Standard Patent Sealed

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