Cycloalkanopyrrolocarbazole derivatives and the use thereof as PARP VEGFR2 and MLK3 inhibitors

Details for Australian Patent Application No. 2007261464 (hide)

Owner Cephalon, Inc.

Inventors Wells, Gregory J.; Diebold, James L.; Hudkins, Robert L.; Dandu, Reddeppareddy; Dunn, Derek; Chatterjee, Sankar; Zulli, Allison L.

Agent Watermark

Pub. Number AU-B-2007261464

PCT Pub. Number WO2007/149451

Priority 11/455,356 19.06.06 US

Filing date 19 June 2007

Wipo publication date 27 December 2007

Acceptance publication date 13 September 2012

International Classifications

C07D 471/14 Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

A61K 31/407 - condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine

A61K 31/41 - having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole

A61K 31/4178

A61K 31/4196 - 1,2,4-Triazoles

A61K 31/427 - not condensed and containing further heterocyclic rings

A61K 31/437

A61K 31/4412 - having oxo groups directly attached to the heterocyclic ring

A61K 31/4439

A61K 31/4453 - only substituted in position 1, e.g. propipocaine, diperodon

A61K 31/497

A61K 31/501 - not condensed and containing further heterocyclic rings

A61K 31/5377

A61P 3/10 Drugs for disorders of the metabolism

A61P 9/10 Drugs for disorders of the cardiovascular system

A61P 15/00 Drugs for genital or sexual disorders

A61P 17/06 Drugs for dermatological disorders

A61P 25/14 Drugs for disorders of the nervous system

A61P 25/16 Drugs for disorders of the nervous system

A61P 25/28 Drugs for disorders of the nervous system

A61P 27/02 Drugs for disorders of the senses

Event Publications

29 January 2009 PCT application entered the National Phase

  PCT publication WO2007/149451 Priority application(s): WO2007/149451

13 September 2012 Application Accepted

  Published as AU-B-2007261464

27 September 2012 Application for Amendment

  The nature of the amendment is: Amend the invention title to read Novel multlcyclic compounds and the use thereof . Address for service in Australia - Watermark Patent and Trade Marks Attorneys Level 2 302 Burwood Road Hawthorn VIC 3122

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