Peptide epoxyketones for proteasome inhibition

Details for Australian Patent Application No. 2007261345 (hide)

Owner Proteolix, Inc.

Inventors Laidig, Guy J.; Bennett, Mark K.; Smyth, Mark S.; Zhou, Han-Jie; Parlati, Francesco; Sylvain, Catherine; Shenk, Kevin D.

Agent Shelston IP

Pub. Number AU-B-2007261345

PCT Pub. Number WO2007/149512

Priority 60/815,218 19.06.06 US

Filing date 19 June 2007

Wipo publication date 27 December 2007

Acceptance publication date 23 February 2012

International Classifications

C07D 303/32 (2006.01) Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom

A61K 31/336 (2006.01) - having three-membered rings, e.g. oxirane, fumagillin

A61K 31/404 (2006.01)

A61K 38/05 (2006.01) Medicinal preparations containing peptides - Dipeptides

A61P 35/00 (2006.01) Antineoplastic agents

A61P 37/00 (2006.01) Drugs for immunological or allergic disorders

C07D 405/12 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07K 5/062 (2006.01) Peptides having up to four amino acids in a fully defined sequence

C07K 5/065 (2006.01) Peptides having up to four amino acids in a fully defined sequence

C07K 5/068 (2006.01) Peptides having up to four amino acids in a fully defined sequence

C07K 5/072 (2006.01) Peptides having up to four amino acids in a fully defined sequence

C07K 5/078 (2006.01) Peptides having up to four amino acids in a fully defined sequence

Event Publications

22 January 2009 PCT application entered the National Phase

  PCT publication WO2007/149512 Priority application(s): WO2007/149512

23 February 2012 Application Accepted

  Published as AU-B-2007261345

21 June 2012 Standard Patent Sealed

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