Owner Vertex Pharmaceuticals Incorporated

Inventors Come, Jon; Binch, Hayley; Yoo, Sanghee; Hadida-Ruah, Sara; Joshi, Pramod; Termin, Andreas; Nanthakumar, Suganthi; Cao, Jingrong; Gutierrez, Corey; Bergeron, Daniele

Agent Baldwins

Pub. Number AU-A-2007258294

PCT Pub. Number WO2007/146349

Priority 60/813,178 13.06.06 US

Filing date 13 June 2007

Wipo publication date 21 December 2007

C07D 277/14 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

A61K 31/4468 (2006.01) - having a nitrogen atom directly attached in position 4, e.g. clebopride, fentanyl

A61K 31/517 (2006.01) - ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine

C07D 417/06 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 417/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 471/10 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 498/10 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 513/10 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups , or