Owner Merck Sharp & Dohme Corp.

Inventors He, Jiafang; Liang, Gui-Bai; Liu, Weiguo; Ge, Min; Yang, Lihu; Walsh, Shawn P.; Lau, Fiona Wai Yu; Lin, Songnian

Agent Spruson & Ferguson

Pub. Number AU-B-2007254325

PCT Pub. Number WO2007/136573

Priority 60/836,308 08.08.06 US; 60/800,542 15.05.06 US

Filing date 11 May 2007

Wipo publication date 29 November 2007

Acceptance publication date 10 May 2012

C07D 213/64 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/343 (2006.01) - condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone

A61K 31/351 (2006.01) - not condensed with another ring

A61K 31/381 (2006.01) - having five-membered rings

A61K 31/427 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/4412 (2006.01) - having oxo groups directly attached to the heterocyclic ring

A61P 1/18 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

C07C 62/34 (2006.01) Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07D 307/93 (2006.01) Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 333/78 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 405/04 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 407/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group

C07D 413/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group