Owner Imperial Innovations Ltd Alnylam Pharmaceuticals, Inc.

Inventors Hardaker, Elizabeth Louise; Birrell, Mark Andrew; Sprague, Andrew; Catley, Matthew Copeland; Belvisi, Maria Gabriela; Fougerolles, Antonin De; Harborth, Jens

Agent Griffith Hack

Pub. Number AU-B-2007253677

PCT Pub. Number WO2007/137220

Priority 60/802,555 22.05.06 US

Filing date 21 May 2007

Wipo publication date 29 November 2007

Acceptance publication date 10 February 2011

A61K 31/7052 (2006.01)

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07H 21/02 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C12N 5/00 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines

C12N 15/113 (2010.01) Mutation or genetic engineering - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

C12N 15/63 (2006.01) Mutation or genetic engineering - Introduction of foreign genetic material using vectors

C12N 15/86 (2006.01) Mutation or genetic engineering - Viral vectors

C12Q 1/70 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving virus or bacteriophage