Owner F. Hoffmann-La Roche AG Genentech, Inc.

Inventors Castanedo, Georgette; Zhu, Bing-Yan; Folkes, Adrian; Sutherlin, Daniel P.; Wan, Nan Chi; Olivero, Alan; Heffron, Tim; Oxenford, Sally; Shuttleworth, Stephen; Gunzner, Janet; Chuckowree, Irina; Mathieu, Simon; Goldsmith, Richard

Agent Davies Collison Cave

Pub. Number AU-B-2007243457

PCT Pub. Number WO2007/127175

Priority 60/795,048 26.04.06 US

Filing date 24 April 2007

Wipo publication date 8 November 2007

Acceptance publication date 23 February 2012

C07D 491/04 (2006.01) Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups , , or

A61K 31/5025 (2006.01) - ortho- or peri-condensed with heterocyclic ring systems

A61P 35/00 (2006.01) Antineoplastic agents

C07D 495/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms

C07D 519/00 (2006.01) Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or