Owner Merck Sharp & Dohme Corp.

Inventors Yang, Zhi-Qiang; Mattern, Mamio Christa; Barrow, James C.; Reger, Thomas S.; Cube, Rowena V.; Bieber, Kelly-Ann S.; Shu, Youheng

Agent Spruson & Ferguson

Pub. Number AU-B-2007238755

PCT Pub. Number WO2007/120729

Priority 60/791,372 12.04.06 US

Filing date 11 April 2007

Wipo publication date 25 October 2007

Acceptance publication date 12 July 2012

C07D 213/40 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/435 - having six-membered rings with one nitrogen as the only ring hetero atom

A61K 31/44 - Non-condensed pyridines

A61K 31/4427 - containing further heterocyclic ring systems

A61P 25/00 Drugs for disorders of the nervous system

C07D 213/61 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/65 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/73 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/74 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/75 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 401/04 Heterocyclic compounds containing two or more hetero rings

C07D 401/12 Heterocyclic compounds containing two or more hetero rings

C07D 401/14 Heterocyclic compounds containing two or more hetero rings

C07D 405/12 Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/12 Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 411/12 Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms

C07D 413/12 Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms