N-hydroxy3-(4-{3-phenyl-s-oxo-propenyl}-phenyl)- acrylamide derivatives and related compounds as histone deacetylase inhibitors for the treatment of cancer

Details for Australian Patent Application No. 2007233732 (hide)

Owner DAC S.R.L.

Inventors Minucci, Saverio; Mai, Antonello; Thaler, Florian; Gagliardi, Stefania; Pain, Gilles; Colombo, Andrea

Agent Fisher Adams Kelly

Pub. Number AU-B-2007233732

PCT Pub. Number WO2007/113249

Priority MI2006A000621 31.03.06 IT

Filing date 30 March 2007

Wipo publication date 11 October 2007

Acceptance publication date 2 February 2012

International Classifications

C07D 295/10 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

A61K 31/4468 (2006.01) - having a nitrogen atom directly attached in position 4, e.g. clebopride, fentanyl

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 31/5375 (2006.01) - 1,4-Oxazines, e.g. morpholine

A61P 35/00 (2006.01) Antineoplastic agents

C07D 211/46 (2006.01) Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 211/58 (2006.01) Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 213/54 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 295/18 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/20 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/22 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

Event Publications

13 November 2008 PCT application entered the National Phase

  PCT publication WO2007/113249 Priority application(s): WO2007/113249

2 February 2012 Application Accepted

  Published as AU-B-2007233732

31 May 2012 Standard Patent Sealed

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