Piperidinyl, indolyl, pirinidyl, morpholinyl and benzimidazolyl urea derivatives as inhibitors of soluble epoxide hydrolase for the treatment of hypertension, inflammations and other diseases

Details for Australian Patent Application No. 2007225170 (hide)

Owner Arete Therapeutics The Regents of the University of California

Inventors Jones, Paul D.; Hammock, Bruce D.; Tsai, Hsing-Ju; Morisseau, Christophe; Huang, Huazhang; Gless Jr., Richard

Agent Pizzeys

Pub. Number AU-B-2007225170

PCT Pub. Number WO2007/106525

Priority 60/782,172 13.03.06 US

Filing date 13 March 2007

Wipo publication date 20 September 2007

Acceptance publication date 1 November 2012

International Classifications

C07D 211/26 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

A61K 31/445 - Non-condensed piperidines, e.g. piperocaine

A61K 31/4523 - containing further heterocyclic ring systems

A61P 9/14 Drugs for disorders of the cardiovascular system

A61P 11/00 Drugs for disorders of the respiratory system

A61P 19/02 Drugs for skeletal disorders

C07C 275/26 Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups

C07C 275/28 Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups

C07D 209/08 Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 211/58 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 211/96 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 213/40 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 295/20 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 401/06 Heterocyclic compounds containing two or more hetero rings

C07D 487/18 Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

Event Publications

11 September 2008 PCT application entered the National Phase

  PCT publication WO2007/106525 Priority application(s): WO2007/106525

1 November 2012 Application Accepted

  Published as AU-B-2007225170

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