Owner Massachusetts Institute of Technology Whitehead Institute For Biomedical Research University of Massachusetts Medical Center MaxPlanck-Gesellschaft zur Forderung der Wissenschaften e.V.

Inventors Bartel, David P.; Sharp, Phillip A.; Tuschi, Thomas; Zamore, Phillip D.

Agent Davies Collison Cave

Pub. Number AU-B-2007214287

Parent 2001249622

Filing date 28 August 2007

Wipo publication date 20 September 2007

Acceptance publication date 19 August 2010

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 31/7105 (2006.01) - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07H 21/00 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C12N 1/00 (2006.01) Micro-organisms, e.g. protozoa

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 15/10 (2006.01) Mutation or genetic engineering - Processes for the isolation, preparation or purification of DNA or RNA

C12N 15/11 (2006.01) Mutation or genetic engineering - DNA or RNA fragments

C12Q 1/02 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving viable micro-organisms

C12Q 1/68 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving nucleic acids

A61K 38/00 (2006.01) Medicinal preparations containing peptides