Owner Amgen Inc.

Inventors Fotsch, Christopher H.; Zhu, Jiawang; Norman, Mark Henry; Han, Nianhe; Chen, Ning; Doherty, Elizabeth M.; Wang, Xianghong; Kelly, Michael G.; Chakrabarti, Partha P.; Liu, Qingyian; Bo, Yunxin Y.

Agent Shelston IP

Pub. Number AU-A-2007200149

Parent 2002364549

Filing date 15 January 2007

Wipo publication date 1 February 2007

C07D 249/18 (2006.01) Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms

A61K 31/17 (2006.01) - having the group NC(O)N or NC(S)N, e.g. urea, thiourea, carmustine

A61K 31/18 (2006.01) - Sulfonamides

A61K 31/343 (2006.01) - condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone

A61K 31/357 (2006.01) - having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel

A61K 31/36 (2006.01)

A61K 31/37 (2006.01)

A61K 31/381 (2006.01) - having five-membered rings

A61K 31/4025 (2006.01) - not condensed and containing further heterocyclic rings, e.g. cromakalim

A61K 31/404 (2006.01)

A61K 31/41 (2006.01) - having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole

A61K 31/415 (2006.01) - 1,2-Diazoles

A61K 31/4184 (2006.01)

A61K 31/4192 (2006.01) - 1,2,3-Triazoles

A61K 31/423 (2006.01) - condensed with carbocyclic rings

A61K 31/428 (2006.01) - condensed with carbocyclic rings

A61K 31/44 (2006.01) - Non-condensed pyridines

A61K 31/4402 (2006.01) - only substituted in position 2, e.g. pheniramine, bisacodyl

A61K 31/4406 (2006.01) - only substituted in position 3, e.g. zimeldine

A61K 31/443 (2006.01)

A61K 31/444 (2006.01)

A61K 31/453 (2006.01)

A61K 31/47 - Quinolines