Biaryl nitrogen heterocycle inhibitors of LTA4H for treating inflammation

Details for Australian Patent Application No. 2006333522 (hide)

Owner deCODE genetics, ehf.

Inventors Sandanayaka, Vincent; Singh, Jasbir; Zhou, Li-Ming; Gurney, Mark

Agent Griffith Hack

Pub. Number AU-A-2006333522

PCT Pub. Number WO2007/078335

Priority 60/752,273 21.12.05 US

Filing date 3 August 2006

Wipo publication date 12 July 2007

International Classifications

C07D 295/15 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

A61K 31/445 (2006.01) - Non-condensed piperidines, e.g. piperocaine

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61P 9/10 (2006.01) Drugs for disorders of the cardiovascular system

A61P 11/06 (2006.01) Drugs for disorders of the respiratory system

A61P 17/06 (2006.01) Drugs for dermatological disorders

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07D 211/58 (2006.01) Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 295/033 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/096 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 333/16 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 333/28 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

Event Publications

24 July 2008 PCT application entered the National Phase

  PCT publication WO2007/078335 Priority application(s): WO2007/078335

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