Substituted Cinnoline derivatives as GABAa-receptor modulators and method for their synthesis

Details for Australian Patent Application No. 2006327300 (hide)

Owner AstraZeneca AB

Inventors Dembofsky, Bruce; Becker, Christopher; Ohnmacht, Cyrus; Chapdelaine, Marc; Chang, Hui-Fang

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-A-2006327300

PCT Pub. Number WO2007/073283

Priority 60/752,137 20.12.05 US; 60/823,693 28.08.06 US

Filing date 18 December 2006

Wipo publication date 28 June 2007

International Classifications

C07D 237/28 (2006.01) Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings

A61K 31/497 (2006.01)

A61K 31/502 (2006.01) - ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61P 25/22 (2006.01) Drugs for disorders of the nervous system

A61P 25/24 (2006.01) Drugs for disorders of the nervous system

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

C07D 401/10 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/10 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

Event Publications

19 June 2008 PCT application entered the National Phase

  PCT publication WO2007/073283 Priority application(s): WO2007/073283

15 December 2011 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This application lapsed under section 142(2)(e). Examination has been requested or an examination report has issued for this application. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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