Heterocyclic-substituted bis-1,8 naphthalimide compounds, antibody drug conjugates, and methods of use

Details for Australian Patent Application No. 2006320945 (hide)

Owner GENENTECH, INC.

Inventors Ha, Edward Hyungsuk; Gazzard, Lewis J.; Um, Joann; Jackson, David Y.

Agent Griffith Hack

Pub. Number AU-B-2006320945

PCT Pub. Number WO2007/064345

Priority 11/311,591 29.11.05 US

Filing date 30 January 2006

Wipo publication date 7 June 2007

Acceptance publication date 7 June 2012

International Classifications

C07D 221/14 (2006.01) Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 35/00 (2006.01) Antineoplastic agents

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

Event Publications

29 May 2008 PCT application entered the National Phase

  PCT publication WO2007/064345 Priority application(s): WO2007/064345

7 June 2012 Application Accepted

  Published as AU-B-2006320945

4 October 2012 Standard Patent Sealed

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