Owner Grunenthal GmbH

Inventors Bahrenberg, Gregor; Christoph, Thomas; Lee, Jeewoo; Schiene, Klaus; Saunders, Derek John; De Vry, Jean; Frank, Robert; Sundermann, Bernd; Ryu, Hyung Chul

Agent Spruson & Ferguson

Pub. Number AU-B-2006303437

PCT Pub. Number WO2007/045462

Priority 60/727,859 19.10.05 US; 10 2005 050 408.6 19.10.05 DE; 10 2005 055 486.5 18.11.05 DE

Filing date 19 October 2006

Wipo publication date 26 April 2007

Acceptance publication date 28 June 2012

C07D 213/40 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/444

A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07D 213/64 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/74 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 295/12 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 311/08 Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings

C07D 401/12 Heterocyclic compounds containing two or more hetero rings

C07D 409/04 Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms