Aminopyrimidine, aminopyridine and aniline derivatives inhibitors of PIM-1 and/or PIM-3

Details for Australian Patent Application No. 2006302174 (hide)

Owner Exelixis, Inc.

Inventors Brown, Samuel David; Koltun, Elena S.; Kearney, Patrick

Agent Davies Collison Cave

Pub. Number AU-A-2006302174

PCT Pub. Number WO2007/044724

Priority 60/724,171 06.10.05 US

Filing date 5 October 2006

Wipo publication date 19 April 2007

International Classifications

C07D 213/81 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/196 (2006.01)

A61K 31/381 (2006.01) - having five-membered rings

A61K 31/41 (2006.01) - having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole

C07C 233/63 (2006.01) Carboxylic acid amides

C07D 257/04 (2006.01) Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms

C07D 307/68 (2006.01) Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 307/93 (2006.01) Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 333/38 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 333/70 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 405/12 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 409/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 413/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

Event Publications

22 May 2008 PCT application entered the National Phase

  PCT publication WO2007/044724 Priority application(s): WO2007/044724

17 July 2008 Amendment Made

  The nature of the amendment is: Amend the invention title to read: Pyridopyrimidinone Inhibitors of PIM-1 and/or PIM-3

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