Potentiation of the therapeutic action of an opioid receptor agonist and/or inhibition or reversal of tolerance to an opioid receptoi agonists using an ultralow dose of an alpha-2 receptor antagonist

Details for Australian Patent Application No. 2006287070 (hide)

Owner Queen's University at Kingston

Inventors Jhamandas, Khem; Milne, Brian

Agent Davies Collison Cave

Pub. Number AU-A-2006287070

PCT Pub. Number WO2007/025383

Priority 60/712,545 30.08.05 US; 60/753,958 23.12.05 US

Filing date 30 August 2006

Wipo publication date 8 March 2007

International Classifications

A61K 31/55 (2006.01) - having seven-membered rings, e.g. azelastine, pentylenetetrazole

A61K 31/137 (2006.01) - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine

A61K 31/4164 (2006.01) - 1,3-Diazoles

A61K 31/4178 (2006.01)

A61K 31/475 (2006.01) - having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine

A61K 31/48 (2006.01) - Ergoline derivatives, e.g. lysergic acid, ergotamine

A61K 31/485 (2006.01) - Morphinan derivatives, e.g. morphine, codeine

A61K 31/5415 (2006.01) - ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam

Event Publications

3 April 2008 PCT application entered the National Phase

  PCT publication WO2007/025383 Priority application(s): WO2007/025383

24 June 2010 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This application lapsed under section 142(2)(a). A direction to request examination has been given for this application. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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