Owner Amgen Inc.

Inventors Rumfelt, Shannon; Bemis, Jean E.; McGowen, David C.; Martin, Matthew W.; Chen, Ning; Kunz, Roxanne; Chaffee, Stuart; Hu, Essa; Dimauro, Erin F.

Agent Wrays

Pub. Number AU-B-2006279372

PCT Pub. Number WO2007/022380

Priority 60/708,720 15.08.05 US; Not given 11.08.06 US

Filing date 15 August 2006

Wipo publication date 22 February 2007

Acceptance publication date 11 November 2010

C07D 239/48 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

A61K 31/44 (2006.01) - Non-condensed pyridines

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07D 213/00 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 237/00 (2006.01) Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 407/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group

C07D 417/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups