Benzimidazole derivatives as sirtuin modulators

Details for Australian Patent Application No. 2006278396 (hide)

Owner Sirtris Pharmaceuticals, Inc.

Inventors Milne, Jill; Nunes, Joseph J.; Vu, Chi B.; Ng, Pui Yee; Bemis, Jean; Xie, Roger; Disch, Jeremy S.

Agent Shelston IP

Pub. Number AU-A-2006278396

PCT Pub. Number WO2007/019416

Priority 60/741,783 02.12.05 US; 60/705,612 04.08.05 US; 60/779,370 03.03.06 US; 60/792,276 14.04.06 US

Filing date 4 August 2006

Wipo publication date 15 February 2007

International Classifications

A61P 3/00 (2006.01) Drugs for disorders of the metabolism

A61K 31/41 (2006.01) - having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole

A61K 31/435 (2006.01) - having six-membered rings with one nitrogen as the only ring hetero atom

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61P 7/00 (2006.01) Drugs for disorders of the blood or the extracellular fluid

A61P 21/00 (2006.01) Drugs for disorders of the muscular or neuromuscular system

A61P 25/00 (2006.01) Drugs for disorders of the nervous system

A61P 27/00 (2006.01) Drugs for disorders of the senses

A61P 35/00 (2006.01) Antineoplastic agents

C07D 235/18 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

Event Publications

28 February 2008 PCT application entered the National Phase

  PCT publication WO2007/019416 Priority application(s): WO2007/019416

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