Owner Asterand UK Limited

Inventors Clark, Kenneth Lyle; Hynd, George; Oxford, Alexander William; Ashton, Mark Richard; Coleman, Robert Alexander; Fenton, Garry; Boyd, Edward Andrew; Harris, Neil Victor; Davis, Richard Jon; Sutton, Jonathan Mark; Brunton, Shirley Ann; Stuttle, Keith Alfred James; Clark, David Edward

Agent Shelston IP

Pub. Number AU-B-2006277786

PCT Pub. Number WO2007/017687

Priority 0516439.7 10.08.05 GB; 60/706,431 09.08.05 US

Filing date 9 August 2006

Wipo publication date 15 February 2007

Acceptance publication date 6 September 2012

C07D 307/42 Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

A61K 31/4418 - having a carbocyclic ring directly attached to the heterocyclic ring, e.g. cyproheptadine

A61P 11/06 Drugs for disorders of the respiratory system

C07C 233/80 Carboxylic acid amides

C07C 257/18 Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines

C07D 213/70 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 263/56 Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings

C07D 307/54 Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 307/91 Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 405/12 Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom