A synthetic route to 14-hydroxyl opiates through 1-halo-thebaine or analogs

Details for Australian Patent Application No. 2006259780 (hide)

Owner Mallinckrodt LLC

Inventors Bao, Jian; Moser, Frank W.; Magparangalan, Daniel P.; Cantrell, Gary L.; Wang, Peter Xianqi

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2006259780

PCT Pub. Number WO2006/138020

Priority 60/691,184 16.06.05 US

Filing date 22 May 2006

Wipo publication date 28 December 2006

Acceptance publication date 12 April 2012

International Classifications

C07D 489/00 (2006.01) Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:

C07D 489/08 (2006.01) Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:

Event Publications

10 January 2008 PCT application entered the National Phase

  PCT publication WO2006/138020 Priority application(s): WO2006/138020

3 November 2011 Assignment before Grant

  Mallinckrodt Inc. The application has been assigned to Mallinckrodt LLC

12 April 2012 Application Accepted

  Published as AU-B-2006259780

9 August 2012 Standard Patent Sealed

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