Cyclohexanesulfonyl derivatives as GlyT1 inhibitors to treat schizophrenia

Details for Australian Patent Application No. 2006256583 (hide)

Owner Merck Sharp & Dohme Limited

Inventors Blackaby, Wesley Peter; Castro Pineiro, Jose Luis; Naylor, Elizabeth Mary; Street, Leslie Joseph; Lewis, Richard Thomas

Agent Spruson & Ferguson

Pub. Number AU-B-2006256583

PCT Pub. Number WO2006/131711

Priority 0511452.5 06.06.05 GB; 0516787.9 17.08.05 GB; 0524968.5 08.12.05 GB

Filing date 5 June 2006

Wipo publication date 14 December 2006

Acceptance publication date 12 January 2012

International Classifications

C07C 317/30 (2006.01) Sulfones

A61K 31/166 (2006.01) - having the carbon atom of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol

A61K 31/4192 (2006.01) - 1,2,3-Triazoles

A61K 31/44 (2006.01) - Non-condensed pyridines

A61K 31/4412 (2006.01) - having oxo groups directly attached to the heterocyclic ring

A61K 31/4439 (2006.01)

A61K 31/505 (2006.01) - Pyrimidines

A61P 25/18 (2006.01) Drugs for disorders of the nervous system

C07D 211/90 (2006.01) Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 213/81 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/82 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 239/28 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 249/04 (2006.01) Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

Event Publications

10 January 2008 PCT application entered the National Phase

  PCT publication WO2006/131711 Priority application(s): WO2006/131711

12 January 2012 Application Accepted

  Published as AU-B-2006256583

10 May 2012 Standard Patent Sealed

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