Owner AstraZeneca AB

Inventors Steelman, Gary; Wang, Xia; Wesolowski, Steven; Smith, Reed W.; Brown, Dean; Urbanek, Rebecca A.; Blackwell, William C.; McLaren, Frances M.; Schnecke, Volker

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2006253049

PCT Pub. Number WO2006/130075

Priority 60/685,832 31.05.05 US

Filing date 29 May 2006

Wipo publication date 7 December 2006

Acceptance publication date 27 May 2010

C07D 451/06 (2006.01) Heterocyclic compounds containing condensed hetero ring systems

A61K 31/44 (2006.01) - Non-condensed pyridines

A61K 31/443 (2006.01)

A61K 31/4436 (2006.01)

A61K 31/46 (2006.01) - 8-Azabicyclo [3.2.1] octane

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61P 3/04 (2006.01) Drugs for disorders of the metabolism

A61P 25/18 (2006.01) Drugs for disorders of the nervous system

A61P 25/24 (2006.01) Drugs for disorders of the nervous system

C07D 211/46 (2006.01) Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 295/12 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 405/04 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 405/12 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms