Owner Amgen Inc.

Inventors Sharma, Rajiv; Zhu, Liusheng; Houze, Jonathan; Sun, Ying; Ma, Zhihua; Medina, Julio C.; Liu, Jiwen; Wang, Yingcai; Schmitt, Michael J.

Agent Shelston IP

Pub. Number AU-B-2006251768

PCT Pub. Number WO2006/127503

Priority 11/436,732 17.05.06 US; 60/683,331 20.05.05 US

Filing date 18 May 2006

Wipo publication date 30 November 2006

Acceptance publication date 10 September 2009

C07D 233/54 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

A61K 31/41 (2006.01) - having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole

A61K 31/4164 (2006.01) - 1,3-Diazoles

A61K 31/4196 (2006.01) - 1,2,4-Triazoles

A61K 31/421 (2006.01) - 1,3-Oxazoles, e.g. pemoline, trimethadione

A61K 31/427 (2006.01) - not condensed and containing further heterocyclic rings

A61P 3/04 (2006.01) Drugs for disorders of the metabolism

A61P 3/06 (2006.01) Drugs for disorders of the metabolism

A61P 3/10 (2006.01) Drugs for disorders of the metabolism

C07D 249/08 (2006.01) Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms

C07D 257/04 (2006.01) Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms

C07D 263/32 (2006.01) Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings

C07D 277/24 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 417/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group