Owner Amgen Inc.

Inventors Choquette, Deborah; Hirai, Satoko; Roveto, Philip; Yang, Kevin; D'amico, Derin C.; D'angelo, Noel; Bauer, David; Xi, Ning; Booker, Shon; Lee, Matthew; Potashman, Michele; Harmange, JeanChristophe; Bellon, Steven; Fellows, Ingrid M.; Germain, Julie; Kim, TaeSeong; Graceffa, Russell; Norman, Mark H.; Liu, Longbin; Boezio, Alessandro; Siegmund, Aaron C.; Dominguez, Celia; La, Daniel

Agent Shelston IP

Pub. Number AU-A-2006239216

PCT Pub. Number WO2006/116713

Priority 60/675,805 27.04.05 US

Filing date 27 April 2006

Wipo publication date 2 November 2006

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61K 31/435 (2006.01) - having six-membered rings with one nitrogen as the only ring hetero atom

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61P 35/00 (2006.01) Antineoplastic agents

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 413/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 495/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms