2-amino-quinazolin-5-ones as HSP90 inhibitors useful in treating proliferation diseases

Details for Australian Patent Application No. 2006236557 (hide)

Owner Novartis Vaccines and Diagnostics Inc.

Inventors Rico, Alice C.; McBride, Christopher; Levine, Barry H.; Lin, Xiaodong; Shafer, Cynthia M.; Wang, X. Michael; Costales, Abran; Bellamacina, Cornelia R.; Antonios-McCrea, William; Machajewski, Timothy D.; McKenna, Maureen; Fong, Susan; Hendrickson, Thomas; Xia, Yi; Doughan, Brandon M.; Zhou, Yasheen; Mendenhall, Kris G.; Gao, Zhenhai

Agent FB Rice

Pub. Number AU-A-2006236557

PCT Pub. Number WO2006/113498

Priority 60/671,662 14.04.05 US

Filing date 14 April 2006

Wipo publication date 26 October 2006

International Classifications

C07D 239/84 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

A61K 31/517 (2006.01) - ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine

A61P 35/00 (2006.01) Antineoplastic agents

C07D 401/04 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/10 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/10 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 413/10 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/10 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 417/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

Event Publications

15 November 2007 PCT application entered the National Phase

  PCT publication WO2006/113498 Priority application(s): WO2006/113498

25 March 2010 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This application lapsed under section 142(2)(a). A direction to request examination has been given for this application. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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