Owner Genentech, Inc.

Inventors Polakis, Paul; Mao, Weiguang

Agent Griffith Hack

Pub. Number AU-B-2006210837

PCT Pub. Number WO2006/083936

Priority 60/756,844 05.01.06 US; 60/648,541 31.01.05 US

Filing date 31 January 2006

Wipo publication date 10 August 2006

Acceptance publication date 12 July 2012

C07K 16/28 Immunoglobulins, e.g. monoclonal or polyclonal antibodies

A61K 39/395 Medicinal preparations containing antigens or antibodies - Antibodies

A61K 47/48 Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 35/00 Antineoplastic agents

C07K 16/30 Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C12N 1/21 Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 15/13 Mutation or genetic engineering - Immunoglobulins

C12N 15/85 Mutation or genetic engineering - for animal cells

G01N 33/574 Investigating or analysing materials by specific methods not covered by groups - for cancer

G01N 33/577 Investigating or analysing materials by specific methods not covered by groups - involving monoclonal antibodies