Owner Vertex Pharmaceuticals Incorporated

Inventors Bebbington, David; Patel, Sanjay; Forster, Cornelia; Li, Pan; Kay, David; Pierce, Albert; Knegtel, Ronald; Wannamaker, Marion; Golec, Julian M. C.; Charrier, Jean-Damien; Davies, Robert; Binch, Haley

Agent Cullen & Co

Pub. Number AU-B-2006201263

Parent 2001290944

Filing date 21 March 2006

Wipo publication date 27 April 2006

Acceptance publication date 30 October 2008

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

A61K 31/4155 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61P 35/00 (2006.01) Antineoplastic agents

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 473/16 (2006.01) Heterocyclic compounds containing purine ring systems

C07D 493/04 (2006.01) Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system

C07D 495/04 (2006.01) Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms

C07D 521/00 (2006.01) Heterocyclic compounds containing unspecified hetero rings