Owner Vertex Pharmaceuticals Incorporated

Inventors Charrier, Jean-Damien; Bebbington, David; Patel, Sanjay; Everitt, Simon; Knegtel, Ronald; Davies, Robert; Kay, David

Agent Cullen & Co

Pub. Number AU-B-2006201229

Parent 2002234047

Filing date 21 March 2006

Wipo publication date 13 April 2006

Acceptance publication date 20 November 2008

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

A61K 31/517 (2006.01) - ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine

A61K 31/519 (2006.01) - ortho- or peri-condensed with heterocyclic rings

A61P 35/00 (2006.01) Antineoplastic agents

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 417/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups